Endocardial fibro-elastosis, mitral incompetence, and coarctation of abdominal aorta.

Congenital mitral incompetence has been only rarely reported as an isolated lesion (Miller, Brown, and Swan, 1964), but may occur as a result of endocardial fibro-elastosis, which is also commonly associated with other anatomical abnormalities, of which coarctation of the aorta is one. The association of congenital mitral incompetence and coarctation of the abdominal aorta has not been reported previously, so we are presenting a family of 3 sibs who had this association of defects. The pathological findings are given in some detail, and the pathology of endocardial fibro-elastosis is reviewed.